Tag Archives: NIH

Dramatic results in TBI research

Rockswolds 1

Dr. Sarah Rockswold and Dr. Gaylan Rockswold


Dr. Gaylan Rockswold and Dr. Sarah Rockswold, along with researchers at the  University of Minnesota and Minneapolis Medical Research Foundation report that the combined use of hyperbaric oxygen (HBO
2) and normobaric hyperoxia (NBH) therapies provides better outcomes in patients with severe traumatic brain injury (TBI) than the standard intensive neurosurgical care recommended for this injury.

“We have never seen this kind of functional outcome improvement in a  TBI study,” explains Dr. Sarah Rockswold. “Combining HBO2 treatments with NBH treatments made a dramatic difference in outcomes.” Continue reading

Autoinjectors offer a way to treat prolonged seizures

HCMC EMS participates in NIH study that finds method safe, effective
for pre-hospital use

Delivering drugs into muscle using an autoinjector, akin to the EpiPen (used to treat serious allergic reactions), is faster and may be a more effective way to stop statusepilepticus (a prolonged seizure lasting longer than five minutes), according to a study sponsored by the National Institutes of Health (NIH). Status epilepticus is a potentially life-threatening emergency that causes 55,000 deaths each year.

Anticonvulsant drugs are typically delivered intravenously (IV) as a first-line treatment for status epilepticus; however, starting an IV in a patient experiencing seizures can pose a challenge for paramedics and waste precious time. Giving an intramuscular shot is easier, faster, and more reliable, especially in patients having convulsions. The researchers sought to determine whether an intramuscular injection, which quickly delivers anticonvulsant medicine into a patient’s thigh muscle, is as safe and effective as giving medicine directly into a vein. The study, which was carried out by paramedics, compared how well delivery by each method stopped patients’ seizures by the time the ambulance arrived at the emergency department. Several local hospitals participated in the 4-year study, but Hennepin Emergency Medical Service (EMS) was the only ambulance service in Minnesota to participate in the Rapid Anticonvulsant Medication Prior to Arrival Trial (RAMPART). RAMPART was conducted through the NINDS’ Neurological Emergencies Treatment Trials (NETT) network conducted locally by researchers at the University of Minnesota. Continue reading